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Independent Study - March 1999

Test results on CR2000 Collagen Type II food supplement:

89.9% of the subjects tested received pain relief at some level within forty-five days of taking Collagen Type II capsules.

Pain syndromes are a part of many people's daily lives. It can render them disabaled in some manner or it can be a degenerative chronic residual from trauma or disease processes. Our objective was to analyse the effectiveness of Collagen Type II verses pacebo treatment and report the results and measure the response by the subjects.

Table 1. Results of response to pain relief by (X) days:

Days to Response

RESPONSE
0-7 DAYS

RESPONSE
8-21 DAYS

RESPONSE
22-45 DAYS

TOTALS

Rheumatory Arthritus

9

6

3

15

Osteoarthritis

7

12

5

24

Fibrositus

4

7

2

13

Lumbosacral w/History
of herniated disc

3

6

3

12

Chronic Post-
Traumatic Pain

2

4

3

9

Gouty Arthritis

2

0

0

2

Cervical Spine w/History
of herniated disc

0

1

1

2

Placebo

0

0

(1)

(1)

Non-responsive

0

0

9

9

TOTALS

27

35

25

89

The total without a response of less pain in forty-five days was three or appox. 10.1% and only one placebo subject recorded a response in forty-five days.

Side effects - Only one subject had nausea. It was noted that he was on other medications as well.

CONCLUSION

Collagen Type II treatment had a significant effect on subjective pain syndromes. Most subjects responded to Collagen Type II in the first 21 days of the trial. Many of these pained subjects had previously been on long-term, pharmaceutical treatment programs. Many subjects responded by initiating life style changes due to lack of pain. Many were excited by the increase in their daily activity. The results have prompted the authors to develop specific disease/pain syndrome trials in the near future.

AUTHORS

Drs. K. Buckman; J. Gutierrez; et. al


FROM Bill Phillips Supplement Review

Over the past few years, scientists have been exploring the possibility that supplementing Collagen Type II may actually help arthritic patients slow the progression of their disease or even halt it. To test this theory, researchers at Harvard Medical School supplemented the diets of arthritic patients with a type of purified Collagen Type II for 3 months.

What this study seemed to indicate is that Collagen supplementation signifigantly reduced swelling and joint pain. Now, some experts have speculated that Collagen Type II may also help prevent the degeneration of joints that occurs with weight-training exercise and have suggested that supplementing your diet with Collagen Type II may actually allow you to build healthier joints.


FROM The Supplement Industry Executive Journal

Five previously published human studies support the use of Hydrolyzed Collagen for maintaining joint function and providing long term pain relief.


Hydrolyzed Collagen Research

Clinical studies conducted in Europe over the past decade, suggest orally administered Hydrolyzed Collagen preparations improve systems associated with joint damage and/or inflammation. Healthy cartilage tissue and joint function depend on a continuous balance of metabolism and renewal of collagen and proteoglycans.

Hydolyzed Collagen studies which involved patients receiving collagen therapy reported improvements with respect to pain intensity. Greater than 90% of the patients reported a "good" or "very good" response with respect to pain and need for medication. Hydrolyzed Collagen powder is clearly safe when administered in suggested amounts, typically 5 to 10 grams per day.

Extensive toxicology evidence indicates that oral consumption of collagen involves no indentifiable health risk. In fact, collagen is regarded by the Food and Drug Administration as a food substance with GRAS (generally regarded as safe) status.

George Clemens, Ph.D., Biology, University of California, Independant Nutrtionist and Bio-medical Consultant.


Doctor Validates the Benefits of CR2000 Unhydrolyzed Collagen Type II + H.A. SmartFormula for Joint Treatment

Los Angeles, CA – Dr. Marc Darrow, an assistant clinical professor of medicine at UCLA medical school has found excellent results with CR2000 (chicken sternum cartilage) Unhydrolyzed Collagen Type II + H.A. SmartFormula, at the Joint Rehabilitation & Sports Medical Center, Los Angeles, CA. Dr. Darrow, known for his innovative prolotherapy treatment, has been supplementing patients with CR2000’s Unhydrolyzed Collagen Type II + H.A. SmartFormula for almost two years with positive response.

CR2000’s Unhydrolyzed Collagen Type II + H.A. SmartFormula is the latest patented product by NeoCell Corp. (exclusively distributed in Canada by CR2000 Collagen - Cell Renew 2000 Inc.) naturally containing Collagen Type II, Chondroiton, Glucosamine, and Hyaluronic Acid for complete joint support. Dr. Darrow is now devising a study to be published.


All Research results on file for viewing.

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